Vitamin D3 receptors are expressed in a variety of tissues, including vascular smooth muscle cells and endothelial cells. The heart is basically a large muscle and like skeletal muscle it has also receptors for vitamin D. At the same time, vitamin D deficiency, prevalent in 30–50% of adults in developed countries. Why are these widespread vitamin D deficiencies of such great concern? Because deficiency increases the risk of a host of chronic diseases, such as osteoporosis, heart disease, some cancers, and multiple sclerosis, as well as infectious diseases, such as tuberculosis and even the seasonal flu.

There are two forms of vitamin D used in supplements: vitamin D2 (“ergocalciferol,” or pre-vitamin D) and vitamin D3 (“cholecalciferol”). Vitamin D3 is chemically indistinguishable from the form of vitamin D naturally produced in the body. Arginext formula includes Vitamin D3 which is 80% more effective than Vitamin D2 ( often used in food products fortified with Vitamin D).

Check Your Vtamin D3

Ask your doctor to check your vitamin D level. You’ll take a simple blood test called 25- hydroxyvitamin D. The measurement is nanograms per milliliter, and it’s generally recommended to keep your levels between 30 and 60 ng/ml. Dr. Erin Michos, Assistant Professor of Medicine at Johns Hopkins Hospital in the Division of Cardiology, suggests that to maintain healthy levels most adults on average probably need 1,000 to 2,000 International Unit (IU) a day.

Vitamin D3 and Cardiovascular Health

A growing number of studies point to vitamin D deficiency as a risk factor for heart attacks, congestive heart failure, peripheral arterial disease (PAD), strokes, and the conditions associated with cardiovascular disease, such as high blood pressure and diabetes. For example, a Harvard study found that people with low vitamin D levels had twice the risk of developing a heart attack compared to those with adequate vitamin D levels.

As Dr Monica Verdoia, M.D. in cardiology, from Eastern Piedmont University in Novara, Italy, concludes, “Present results suggest vitamin D deficiency to be the cause rather than the consequence of atherosclerosis,” Recent evidence of many studies also suggest that Vitamin D supplementation secures better survival, specifically in patients with documented deficiency.

Other Vitamin D3 Benefits

Vitamin D is good for the bones. healthy levels of Vitamin D prevent rickets in children, Several studies link low vitamin D levels with a risk of bone fractures in older adul. They suggest that vitamin D supplementation may reduced hip and non-spine fractures by 20 percent as long as vitamin D is taken in a dose of 800 IU per day. Some studies found that taking Vitamin D supplements reduces the likelihood of Multiple Sclerosis. It was also found that many tumors developed in breast, skin, lung and colon also contain vitamin D receptors therefore they are directly affected by increased of vitamin D in the body. It appears that vitamin D can inhibit proliferation of a number of cancerous cells Vitamin D also help increase muscle strength that helps to prevent falls – a common problem in older people. Researchers found that taking up to 1,000 IU of vitamin D per day lowered the risk of falls by 19 percent.
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